Malignant Peripheral Nerve Sheath Tumour– A Rare Malignancy in Mandible

Malignant peripheral nerve sheath tumour (MPNST) is biologically an aggressive tumour that is usually found in the extremities, trunk and infrequently found in the head and neck area, particularly in the jaws, arising from the cells associated with nerve sheath. MPNST of the mandible is a very uncommon tumour that develops either from a pre-existing neurofibroma orde novo. Because of the greater variability from one case to the next in overall appearance both clinically and histologically, a case of MPNST of the mandible in 25-year-old female patient is reported.

Bronchial foreign bodies.

Foreign body aspiration is an extremely serious problem in childhood with varied clinical presentation demanding high degree of suspicion on the part of clinician. Surgical emphysema of the neck and chest often complicates tracheostomy and sharp penetrating injuries to the neck perforating viscera of the aerodigestive tract. Rarely if follows chest injuries. But emphysema due to the neck of foreign bodies in the bronchus is quite rare. The authors hereby report four cases of surgical emphysema following foreign body aspiration into the tracheobronchial tree.

Choanal atresia: transnasal endoscopic technique.

OBJECTIVE: This article attempts to address the controversy between, endoscopic and traditional approaches to neonatal choanal atresia. METHOD: Congenital choanal atresia has been recognized for over 200 years, first described by Roedere in 1775. This condition is uncommon, occurring in approximately 1 in 7000 live births. Unfortunately a single ideal procedure for this condition does not exist. RESULTS: Stankiewicz is credited with the first description of endoscopic techniques for choanal atresia repair. All patients diagnosed to have choanal atresia, treated between 1999 and 2000 were reviewed. Out of four patients two underwent endoscopic repair. CONCLUSION: Transnasal endoscopic technique is followed by stenting with endotracheal portex tubes for 4-6 weeks in the initial surgical procedure of choice.

Tracheobronchial foreign bodies.

OBJECTIVE: [corrected] Foreign body inhalation is an extremely serious problem in children and sometimes result in sudden death. The current mortality rate from foreign body inhalation is between 0% and 1.8% according to various studies. In spite of this, undiagnosed and unsuspected foreign bodies still occur in the airway. METHODS: Pediatric patients with documented foreign body inhalation, treated in the Department of Pediatrics, Bapuji Hospital, JJM Medical College during 1997-2000 are included in the analysis. Children with or without positive history of aspiration were examined and the diagnosis was made on the basis of history, clinical findings, radilogic evaluation and strong index of suspicion in those children where reasonable appropriate treatment failed to resolve the respiratory symptoms. Bronchoscopy was performed for a suspected foreign body on 165 children. RESULT: A review of 165 pediatric cases of suspected foreign body aspiration revealed, children between 1 and 3 years were found to be very vulnerable for aspiration. Majority of children were boys. Over 70% of the patients had positive history of inhalation. Only 60% of the patients presented immediately, that is within 24 hours after aspiration. Common symptoms were cough and respiratory distress. Physical examination showed abnormal finding in 91% of cases. Decreased air entry was the significant clinical sign. Obstructive emphysema was found in majority of the cases (49.5%). Rigid bronchoscopy under general anaesthesia was the preferred method for removal of aspirated foreign body. In 65 (61.9%) cases foreign body was lodged in the right main bronchus and majority of these were organic in nature, that is 96 (91.43%). CONCLUSION: Tracheobronchial foreign bodies should be strongly suspected in pediatric age group who present with a suggestive history, even when physical and radiographic evidence is absent. The modalities of diagnosis, management and outcome are discussed.